Press Releases

First Patients Treated in Italy with the Percutianeous MitraClip® System (October 21, 2008)

Evalve Expands Executive Leadership Team (October 9, 2008)

Evalve Announces Enrollment Completion of the Everest Randomized Study (September 30, 2008)

First European Patients Treated with the Percutaneous MitraClip® System (September 23, 2008)

MitraClip® Device Preliminary Data Suggests Improved Heart Function and Relief from Heart Failure Symptoms in Functional Mitral Regurgitation Patients (April 1, 2008)

Evalve Announces CE Mark Approval of the World's First Percutaneous Valve Repair System (March 25, 2008)

Evalve Completes $60 Million Series D Financing (Dec. 4, 2007)

New Data Shows Ongoing Benefits of Percutaneous MitraClip® Device for Patients with Mitral Regurgitation (Oct. 24, 2007)

Evalve's Percutaneous MitraClip® Device Results in Significant Reverse Left Ventricular Remodeling (March 26, 2007)

High Risk Patients Gain Access to Percutaneous MitraClip® Device to Reduce MR (March 19 , 2007)

Evalve Announces New Data Showing its First-in-Class Percutaneous MitraClip® Device Reduces Mitral Regurgitation without Surgery (Oct. 25, 2006)

Evalve Announces Initiation of Pivotal Trial of Percutaneous Alternative to Open-Heart Mitral Valve Surgery. (Oct. 17, 2005)

New Device Brings Hope to Severe Heart Disease Patients. (Oct. 17, 2005)

Six-month Data Supports Further Study of Clip Device for Non-surgical Mitral Valve Repair (March 7, 2005)

Researchers Report Favorable Preliminary Results with Percutaneous Mitral Valve Repair. (Sept. 30, 2004)

Evalve, Inc. Announces Completion of a $35 Million Series C Financing. (May 24, 2004)

Preliminary experience with clip described at ACC. (March 9, 2004)

New Endovascular Procedure May Spare Patients Suffering. (Sept. 15, 2003)

Clip Device Accomplishes Endovascular Non-Surgical Repair of Faulty Heart Valve. (Sept. 15, 2003)

Publications

Elyse Foster, MD, Hal S. Wasserman, MD, William Gray, MD, Shunichi Homma, MD, Marco R. Di Tullio, MD, Leonardo Rodriguez, MD, William J. Stewart, MD, Patrick Whitlow, MD, Peter Block, MD, Randy Martin, MD, John Merlino, MD, Howard C. Herrmann, MD, Susan E. Wiegers, MD, Frank E. Silvestry, MD, Andrew Hamilton, MD, Alan Zunamon, MD, Kimberly Kraybill, MD, Ivor L. Gerber, MD, Sarah G. Weeks, MD, Yan Zhang, MD, and Ted Feldman, MD, Quantitative Assessment of Severity of Mitral Regurgitation by Serial Echocardiography in a Multi-center Clinical Trial of Percutaneous Mitral Valve Repair, Am J Cardiology 2007; 100:1577-1583.

Frank E. Silvestry, MD, FASE, L. Leonardo Rodriguez, MD, Howard C. Herrmann, MD, Sameer Rohatgi, MD, Stuart J . Weiss, MD, P h D, William J. Stewart, MD, FASE, Shunichi Homma, MD, Neil Goyal, MD, T odd Pulerwitz, MD, Alan Zunamon, MD, Andrew Hamilton, MD, John Merlino, MD, Randolph Martin, MD, FASE, Kimberly Krabill, MD, Peter C. B loc k, MD, P at Whitlow, MD, E. Murat Tuzcu, MD, Samir Kapadia, MD, William A. G ray, MD, Mark Reisman, MD, Hal Wasserman, MD, Allan Schwartz, MD, Elyse Foster, MD, Ted Feldman, MD, and Susan E. Wiegers, MD, FASE. Echocardiographic Guidance and Assessment of Percutaneous Repair for Mitral Regurgitation with the Evalve MitraClip®: Lessons Learned from EVEREST I, J Am Soc Echocardiography 2007; 20:1131-1140.

Fann JI, St Goar FG, Komtebedde J, Oz MC, Block PC, Foster E, Butany J, Feldman T, Burdon TA. Beating heart catheter-based edge-to-edge mitral valve procedure in a porcine model: efficacy and healing response. Circulation. 2004 Aug 24;110(8):988-93. Epub 2004 Aug 9.

St Goar FG, Fann JI, Komtebedde J, Foster E, Oz MC, Fogarty TJ, Feldman T, Block PC. Endovascular edge-to-edge mitral valve repair: short-term results in a porcine model. Circulation. 2003 Oct 21;108(16):1990-3. Epub 2003 Oct 6.

Dang NC, Aboodi MS, Sakaguchi T, Wasserman HS, Argenziano M, Cosgrove DM, Rosengart TK, Feldman T, Block PC, Oz MC. Surgical revision after percutaneous mitral valve repair with a clip: initial multicenter experience. Ann Thorac Surg. 2005 Dec;80(6):2338-42.

Feldman T, Wasserman HS, Herrmann HC, Gray W, Block PC, Whitlow P, St Goar F, Rodriguez L, Silvestry F, Schwartz A, Sanborn TA, Condado JA, Foster E. Percutaneous mitral valve repair using the edge-to-edge technique: six-month results of the EVEREST Phase I Clinical Trial. J Am Coll Cardiol. 2005 Dec 6;46(11):2134-40. Epub 2005 Oct 19.

Herrmann HC, Rohatgi S, Wasserman HS, Block P, Gray W, Hamilton A, Zunamon A, Homma S, Di Tullio MR, Kraybill K, Merlino J, Martin R, Rodriguez L, Stewart WJ, Whitlow P, Wiegers SE, Silvestry FE, Foster E, Feldman T. Mitral valve hemodynamic effects of percutaneous edge-to-edge repair with the MitraClip® device for mitral regurgitation. Catheter Cardiovasc Interv. 2006 Dec;68(6):821-8.

Within the United States: Investigational Device. Limited by United States law to investigational use. Within Canada: Investigational Device. To Be Used by Qualified Investigators Only – Instrument de recherche. Réservé uniquement à l'usage de chercheurs compétents.

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